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Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $51 | In Stock | |
5 mg | $82 | In Stock | |
10 mg | $124 | In Stock | |
25 mg | $224 | In Stock | |
50 mg | $332 | In Stock | |
100 mg | $497 | In Stock | |
200 mg | $678 | In Stock | |
1 mL x 10 mM (in DMSO) | $97 | In Stock |
Description | Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism. The IC50 values of perhexiline maleate against rat heart and liver CPT 1 were 77 and 148 μM, respectively. |
In vitro | Perhexiline treatment increases the susceptibility of NB cells to antiblastic treatments. Co-administration of Perhexiline maleate potentiates the efficacy of cisplatin to reduce the in vitro clonogenic potential of NB cells[2]. |
In vivo | The co-administration of Perhexiline and cisplatin yields a clear enhancement of antitumor effects, resulting in a significantly improved progression-free survival as compared with mice treated with DMSO. |
Molecular Weight | 393.56 |
Formula | C23H39NO4 |
Cas No. | 6724-53-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 27.5 mg/mL (69.87 mM) ![]() | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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